Structural Modeling and in Silico Screening of Potential Small-Molecule Allosteric Agonists of a Glucagon-like Peptide 1 Receptor

[Image: see text] The glucagon-like peptide 1 receptor (GLP-1R) belongs to the pharmaceutically important class B family of G-protein-coupled receptors (GPCRs), and its incretin peptide ligand GLP-1 analogs are adopted drugs for the treatment of type 2 diabetes. Despite remarkable antidiabetic effec...

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Detalles Bibliográficos
Autores principales: Redij, Tejashree, Chaudhari, Rajan, Li, Zhiyu, Hua, Xianxin, Li, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648429/
https://www.ncbi.nlm.nih.gov/pubmed/31459371
http://dx.doi.org/10.1021/acsomega.8b03052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648429/
https://www.ncbi.nlm.nih.gov/pubmed/31459371
http://dx.doi.org/10.1021/acsomega.8b03052

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