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Targeting Translation Activity at the Ribosome Interface with UV-Active Small Molecules
[Image: see text] Puromycin is a well-known antibiotic that is used to study the mechanism of protein synthesis and to monitor ribosome activity due to its incorporation into nascent peptide chains. However, puromycin effects outside the ribosome catalytic core remain unexplored. Here, we developed...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648492/ https://www.ncbi.nlm.nih.gov/pubmed/31460127 http://dx.doi.org/10.1021/acsomega.9b00366 |