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Total Synthesis of (±)-Quinagolide: A Potent D(2) Receptor Agonist for the Treatment of Hyperprolactinemia
[Image: see text] A potent dopamine (D(2)) receptor agonist (±)-quinagolide, which is used for the treatment of hyperprolactinemia, was synthesized using the ring closing metathesis (RCM) approach from meta-hydroxybenzaldehyde as the starting material. The key features of this synthesis are pyrolyti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648496/ https://www.ncbi.nlm.nih.gov/pubmed/31459911 http://dx.doi.org/10.1021/acsomega.9b00903 |