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Total Synthesis of (±)-Quinagolide: A Potent D(2) Receptor Agonist for the Treatment of Hyperprolactinemia

[Image: see text] A potent dopamine (D(2)) receptor agonist (±)-quinagolide, which is used for the treatment of hyperprolactinemia, was synthesized using the ring closing metathesis (RCM) approach from meta-hydroxybenzaldehyde as the starting material. The key features of this synthesis are pyrolyti...

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Detalles Bibliográficos
Autores principales: Chavan, Subhash P., Kadam, Appasaheb L., Kawale, Sanket A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648496/
https://www.ncbi.nlm.nih.gov/pubmed/31459911
http://dx.doi.org/10.1021/acsomega.9b00903