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Computational Studies on the Nonenzymatic Deamidation Mechanisms of Glutamine Residues

[Image: see text] The nonenzymatic deamidation reactions of asparagine (Asn) and glutamine (Gln) residues in proteins are associated with protein turnover and age-related diseases. The reactions are also believed to provide a molecular clock for biological processes. Although Gln deamidation is assu...

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Detalles Bibliográficos
Autores principales: Kato, Koichi, Nakayoshi, Tomoki, Kurimoto, Eiji, Oda, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648516/
https://www.ncbi.nlm.nih.gov/pubmed/31459565
http://dx.doi.org/10.1021/acsomega.8b03199