Organocatalytic Enantioselective Mannich Reaction: Direct Access to Chiral β-Amino Esters

[Image: see text] An asymmetric Mannich reaction has been developed to generate chiral β-amino esters in good yields with excellent enantiomeric excesses (ee, up to 99%) using a chiral bifunctional thiourea catalyst derived from (R,R)-cyclohexyldiamine. This is the first report on the addition of 3-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravi Kumar, G., Ramesh, Boora, Yarlagadda, Suresh, Sridhar, Balasubramanian, Reddy, B. V. Subba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648529/
https://www.ncbi.nlm.nih.gov/pubmed/31459463
http://dx.doi.org/10.1021/acsomega.8b02132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648529/
https://www.ncbi.nlm.nih.gov/pubmed/31459463
http://dx.doi.org/10.1021/acsomega.8b02132

Ejemplares similares