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Organocatalytic Enantioselective Mannich Reaction: Direct Access to Chiral β-Amino Esters
[Image: see text] An asymmetric Mannich reaction has been developed to generate chiral β-amino esters in good yields with excellent enantiomeric excesses (ee, up to 99%) using a chiral bifunctional thiourea catalyst derived from (R,R)-cyclohexyldiamine. This is the first report on the addition of 3-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648529/ https://www.ncbi.nlm.nih.gov/pubmed/31459463 http://dx.doi.org/10.1021/acsomega.8b02132 |