Direct Functionalization of C(sp(2))–H Bond in Nonaromatic Azaheterocycles: Palladium-Catalyzed Cross-Dehydrogenative Coupling (CDC) of 2H-Imidazole 1-Oxides with Pyrroles and Thiophenes

[Image: see text] The C(sp(2))–H bond functionalization methodology was first applied to carry out the palladium-catalyzed oxidative C–H/C–H coupling reactions of 2H-imidazole 1-oxides with pyrroles and thiophenes. As a result, a number of novel 5-heteroarylated 2H-imidazole 1-oxides, which are of p...

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Detalles Bibliográficos
Autores principales: Akulov, Alexey A., Varaksin, Mikhail V., Charushin, Valery N., Chupakhin, Oleg N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648547/
https://www.ncbi.nlm.nih.gov/pubmed/31459361
http://dx.doi.org/10.1021/acsomega.8b02916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648547/
https://www.ncbi.nlm.nih.gov/pubmed/31459361
http://dx.doi.org/10.1021/acsomega.8b02916

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