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Dehydrative Transformation of Spirooxindoles to Pyrido[2,3-b]indoles via POCl(3)
[Image: see text] A two-step one-pot efficient synthesis of pyrido[2,3-b]indoles via reaction between isatin, α-amino acid, and dipolarophile has been developed. The initial 1,3-dipolar cycloaddition between the reactants that is performed in the presence of either CuI or methanol results in spiroox...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648575/ https://www.ncbi.nlm.nih.gov/pubmed/31459716 http://dx.doi.org/10.1021/acsomega.9b00396 |