Synthesis and Characterization in Rodent Brain of the Subtype-Selective NR2B NMDA Receptor Ligand [(11)C]Ro04-5595 as a Potential Radiotracer for Positron Emission Tomography

[Image: see text] The NR2B subunit of the N-methyl-d-aspartate (NMDA) receptor has been implicated in controlling synaptic plasticity, memory, and learning. Herein, we describe an (11)C-labeled PET radiotracer based on 1-(4-chlorophenethyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol, Ro04...

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Detalles Bibliográficos
Autores principales: Jakobsson, Jimmy E., Gourni, Eleni, Khanapur, Shivashankar, Brito, Beatriz, Riss, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648642/
https://www.ncbi.nlm.nih.gov/pubmed/31460083
http://dx.doi.org/10.1021/acsomega.9b00357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648642/
https://www.ncbi.nlm.nih.gov/pubmed/31460083
http://dx.doi.org/10.1021/acsomega.9b00357

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