Asymmetric Synthesis of Spirocyclopentane Oxindoles Containing Four Consecutive Stereocenters and Quaternary α-Nitro Esters via Organocatalytic Enantioselective Michael–Michael Cascade Reactions

[Image: see text] An enantioselective domino Michael–Michael reaction of nitroolefins and 2-nitro-3-arylacrylates has been established, which provided a series of spirocyclopentane oxindoles with four consecutive stereocenters including quaternary α-nitro esters with good yields (up to 73%) and exce...

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Detalles Bibliográficos
Autores principales: Chaudhari, Prakash D., Hong, Bor-Cherng, Wen, Chao-Lin, Lee, Gene-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648780/
https://www.ncbi.nlm.nih.gov/pubmed/31459355
http://dx.doi.org/10.1021/acsomega.8b03049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648780/
https://www.ncbi.nlm.nih.gov/pubmed/31459355
http://dx.doi.org/10.1021/acsomega.8b03049

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