Potent CYP3A4 Inhibitors Derived from Dillapiol and Sesamol

[Image: see text] Synthesis of 50 analogues of the natural insecticide synergists, dillapiol and sesamol, is reported. These were evaluated as potential insecticide synergists based on their inhibition of human CYP3A4. The most potent inhibitors have a relatively large hydrophobic substituent at eit...

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Detalles Bibliográficos
Autores principales: Francis Carballo-Arce, Ana, Raina, Vikrant, Liu, Suqi, Liu, Rui, Jackiewicz, Victoria, Carranza, David, Arnason, John Thor, Durst, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648837/
https://www.ncbi.nlm.nih.gov/pubmed/31460189
http://dx.doi.org/10.1021/acsomega.9b00897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648837/
https://www.ncbi.nlm.nih.gov/pubmed/31460189
http://dx.doi.org/10.1021/acsomega.9b00897

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