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Potent CYP3A4 Inhibitors Derived from Dillapiol and Sesamol
[Image: see text] Synthesis of 50 analogues of the natural insecticide synergists, dillapiol and sesamol, is reported. These were evaluated as potential insecticide synergists based on their inhibition of human CYP3A4. The most potent inhibitors have a relatively large hydrophobic substituent at eit...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648837/ https://www.ncbi.nlm.nih.gov/pubmed/31460189 http://dx.doi.org/10.1021/acsomega.9b00897 |