Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression

The eIF4E-homologous protein (4EHP) is a translational repressor that competes with eIF4E for binding to the 5′-cap structure of specific mRNAs, to which it is recruited by protein factors such as the GRB10-interacting GYF (glycine-tyrosine-phenylalanine domain) proteins (GIGYF). Several experimenta...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruscica, Vincenzo, Bawankar, Praveen, Peter, Daniel, Helms, Sigrun, Igreja, Cátia, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648886/
https://www.ncbi.nlm.nih.gov/pubmed/31114929
http://dx.doi.org/10.1093/nar/gkz429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648886/
https://www.ncbi.nlm.nih.gov/pubmed/31114929
http://dx.doi.org/10.1093/nar/gkz429

Ejemplares similares