TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2

Background: The co-inhibitory receptor PD-1 is expressed in many tumors including head and neck squamous cell carcinoma (HNSCC) and is an important immunotherapy target. However, the role of PD-1 ligands, PD-L1, and particularly PD-L2, in the tumor-stromal cell interactions that cause a tumor-permis...

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Detalles Bibliográficos
Autores principales: Baruah, Paramita, Bullenkamp, Jessica, Wilson, Philip O. G., Lee, Michael, Kaski, Juan Carlos, Dumitriu, Ingrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648892/
https://www.ncbi.nlm.nih.gov/pubmed/31379843
http://dx.doi.org/10.3389/fimmu.2019.01644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648892/
https://www.ncbi.nlm.nih.gov/pubmed/31379843
http://dx.doi.org/10.3389/fimmu.2019.01644

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