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M1 Macrophages Induce PD-L1 Expression in Hepatocellular Carcinoma Cells Through IL-1β Signaling

Hepatocellular carcinoma (HCC) is a prototype of inflammation-related cancer, harboring M1-like and M2-like tumor-associated macrophages. M1 macrophages are thought to be tumoricidal, but some studies report its pro-tumor role. The programmed cell death-ligand (PD-L) 1 expressed in HCC cells is a cr...

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Detalles Bibliográficos
Autores principales: Zong, Zhaoyun, Zou, Jiahuan, Mao, Rudi, Ma, Chao, Li, Na, Wang, Jianing, Wang, Xiaoyan, Zhou, Huaiyu, Zhang, Lining, Shi, Yongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648893/
https://www.ncbi.nlm.nih.gov/pubmed/31379842
http://dx.doi.org/10.3389/fimmu.2019.01643