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Structures and mechanism of transcription initiation by bacterial ECF factors

Bacterial RNA polymerase (RNAP) forms distinct holoenzymes with extra-cytoplasmic function (ECF) σ factors to initiate specific gene expression programs. In this study, we report a cryo-EM structure at 4.0 Å of Escherichia coli transcription initiation complex comprising σ(E)—the most-studied bacter...

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Detalles Bibliográficos
Autores principales: Fang, Chengli, Li, Lingting, Shen, Liqiang, Shi, Jing, Wang, Sheng, Feng, Yu, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648896/
https://www.ncbi.nlm.nih.gov/pubmed/31131408
http://dx.doi.org/10.1093/nar/gkz470