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Computational Prediction of the Mode of Binding of Antitumor Lankacidin C to Tubulin
[Image: see text] Lankacidin C, which is an antibiotic produced by the organism Streptomyces rochei, shows considerable antitumor activity. The mechanism of its antitumor activity remained elusive for decades until it was recently shown to overstabilize microtubules by binding at the taxol binding s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648929/ https://www.ncbi.nlm.nih.gov/pubmed/31459641 http://dx.doi.org/10.1021/acsomega.8b03470 |