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Examining the Impact of Antimicrobial Fluoroquinolones on Human DNA Topoisomerase IIα and IIβ

[Image: see text] Fluoroquinolones are a class of widely prescribed antibiotics with a broad range of activity against Gram-positive, Gram-negative, and some atypical microbes. Unfortunately, these drugs are associated with significant adverse events including neuropathy, tendinopathy, cardiac rhyth...

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Detalles Bibliográficos
Autores principales: Fief, Cole A., Hoang, Kristine G., Phipps, Stephen D., Wallace, Jessica L., Deweese, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648947/
https://www.ncbi.nlm.nih.gov/pubmed/31459613
http://dx.doi.org/10.1021/acsomega.8b03428