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Consequences of Heterogeneous Crowding on an Enzymatic Reaction: A Residence Time Monte Carlo Approach

[Image: see text] Translational diffusion of a free substrate in crowded metabolically active spaces such as cell cytoplasm or mitochondrial matrix is punctuated by collisions and nonspecific interactions with soluble/immobile macromolecules/macrostructures in a variety of shapes/sizes. It is not un...

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Detalles Bibliográficos
Autores principales: Anand, Rajat, Agrawal, Manish, Mattaparthi, Venkata Satish Kumar, Swaminathan, Rajaram, Santra, Sitangshu Bikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649177/
https://www.ncbi.nlm.nih.gov/pubmed/31459357
http://dx.doi.org/10.1021/acsomega.8b02863