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Consequences of Heterogeneous Crowding on an Enzymatic Reaction: A Residence Time Monte Carlo Approach
[Image: see text] Translational diffusion of a free substrate in crowded metabolically active spaces such as cell cytoplasm or mitochondrial matrix is punctuated by collisions and nonspecific interactions with soluble/immobile macromolecules/macrostructures in a variety of shapes/sizes. It is not un...
Autores principales: | Anand, Rajat, Agrawal, Manish, Mattaparthi, Venkata Satish Kumar, Swaminathan, Rajaram, Santra, Sitangshu Bikas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649177/ https://www.ncbi.nlm.nih.gov/pubmed/31459357 http://dx.doi.org/10.1021/acsomega.8b02863 |
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