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Effects of antiepileptic drugs in a new TSC/mTOR‐dependent epilepsy mouse model

OBJECTIVE: An epilepsy mouse model for Tuberous Sclerosis Complex (TSC) was developed and validated to investigate the mechanisms underlying epileptogenesis. Furthermore, the possible antiepileptogenic properties of commonly used antiepileptic drugs (AEDs) and new compounds were assessed. METHODS: T...

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Detalles Bibliográficos
Autores principales: Koene, Linda M. C., van Grondelle, Saskia E., Proietti Onori, Martina, Wallaard, Ilse, Kooijman, Nathalie H. R. M., van Oort, Annabel, Schreiber, Jadwiga, Elgersma, Ype
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649373/
https://www.ncbi.nlm.nih.gov/pubmed/31353861
http://dx.doi.org/10.1002/acn3.50829