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Effects of antiepileptic drugs in a new TSC/mTOR‐dependent epilepsy mouse model
OBJECTIVE: An epilepsy mouse model for Tuberous Sclerosis Complex (TSC) was developed and validated to investigate the mechanisms underlying epileptogenesis. Furthermore, the possible antiepileptogenic properties of commonly used antiepileptic drugs (AEDs) and new compounds were assessed. METHODS: T...
Autores principales: | Koene, Linda M. C., van Grondelle, Saskia E., Proietti Onori, Martina, Wallaard, Ilse, Kooijman, Nathalie H. R. M., van Oort, Annabel, Schreiber, Jadwiga, Elgersma, Ype |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649373/ https://www.ncbi.nlm.nih.gov/pubmed/31353861 http://dx.doi.org/10.1002/acn3.50829 |
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