Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s disease

Neuropathological studies showed early locus coeruleus (LC) neuronal loss associated with tauopathy in Alzheimer’s Disease (AD). We used the LC signal intensity (LC‐I) on 3T MRI to assess the LC integrity in AD (n = 37) and controls (n = 17). The LC‐I was decreased in AD regardless of typical (amnes...

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Detalles Bibliográficos
Autores principales: Olivieri, Pauline, Lagarde, Julien, Lehericy, Stéphane, Valabrègue, Romain, Michel, Adeline, Macé, Pierre, Caillé, Fabien, Gervais, Philippe, Bottlaender, Michel, Sarazin, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649639/
https://www.ncbi.nlm.nih.gov/pubmed/31353860
http://dx.doi.org/10.1002/acn3.50818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649639/
https://www.ncbi.nlm.nih.gov/pubmed/31353860
http://dx.doi.org/10.1002/acn3.50818

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