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A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

Human T cell autoreactivity toward lipid antigens presented by CD1 proteins can manifest in numerous diseases, including psoriasis, contact hypersensitivities, and allergies. However, the molecular mechanisms for regulating T cell autoreactivity toward lipid antigens remain unclear. We determined th...

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Detalles Bibliográficos
Autores principales: Shahine, Adam, Van Rhijn, Ildiko, Cheng, Tan-Yun, Iwany, Sarah, Gras, Stephanie, Moody, D. Branch, Rossjohn, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649662/
https://www.ncbi.nlm.nih.gov/pubmed/29054999
http://dx.doi.org/10.1126/sciimmunol.aao1384