Cargando…
A molecular basis of human T cell receptor autoreactivity toward self-phospholipids
Human T cell autoreactivity toward lipid antigens presented by CD1 proteins can manifest in numerous diseases, including psoriasis, contact hypersensitivities, and allergies. However, the molecular mechanisms for regulating T cell autoreactivity toward lipid antigens remain unclear. We determined th...
Autores principales: | Shahine, Adam, Van Rhijn, Ildiko, Cheng, Tan-Yun, Iwany, Sarah, Gras, Stephanie, Moody, D. Branch, Rossjohn, Jamie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649662/ https://www.ncbi.nlm.nih.gov/pubmed/29054999 http://dx.doi.org/10.1126/sciimmunol.aao1384 |
Ejemplares similares
-
αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b
por: Farquhar, Rachel, et al.
Publicado: (2022) -
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
por: Shahine, Adam, et al.
Publicado: (2019) -
CD1a autoreactive T cells recognize natural skin oils that function as headless antigens
por: de Jong, Annemieke, et al.
Publicado: (2013) -
T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
por: Gras, Stephanie, et al.
Publicado: (2016) -
CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire
por: de Jong, Annemieke, et al.
Publicado: (2010)