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Disordered region of H3K9 methyltransferase Clr4 binds the nucleosome and contributes to its activity

Heterochromatin is a distinctive chromatin structure that is essential for chromosome segregation, genome stability and regulation of gene expression. H3K9 methylation (H3K9me), a hallmark of heterochromatin, is deposited by the Su(var)3-9 family of proteins; however, the mechanism by which H3K9 met...

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Detalles Bibliográficos
Autores principales: Akoury, Elias, Ma, Guoli, Demolin, Segolene, Brönner, Cornelia, Zocco, Manuel, Cirilo, Alexandre, Ivic, Nives, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649693/
https://www.ncbi.nlm.nih.gov/pubmed/31165882
http://dx.doi.org/10.1093/nar/gkz480