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Solvent viscosity facilitates replication and ribozyme catalysis from an RNA duplex in a model prebiotic process
The RNA World hypothesis posits that RNA was once responsible for genetic information storage and catalysis. However, a prebiotic mechanism has yet to be reported for the replication of duplex RNA that could have operated before the emergence of polymerase ribozymes. Previously, we showed that a vis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649698/ https://www.ncbi.nlm.nih.gov/pubmed/31170298 http://dx.doi.org/10.1093/nar/gkz496 |