A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation

Retinoic acid (RA) induces rapid differentiation of embryonic stem cells (ESCs), partly by activating expression of the transcription factor Hoxa1, which regulates downstream target genes that promote ESCs differentiation. However, mechanisms of RA-induced Hoxa1 expression and ESCs early differentia...

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Detalles Bibliográficos
Autores principales: Su, Guangsong, Guo, Dianhao, Chen, Jun, Liu, Man, Zheng, Jian, Wang, Wenbin, Zhao, Xueyuan, Yin, Qingqing, Zhang, Lei, Zhao, Zhongfang, Shi, Jiandang, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649716/
https://www.ncbi.nlm.nih.gov/pubmed/31147716
http://dx.doi.org/10.1093/nar/gkz482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649716/
https://www.ncbi.nlm.nih.gov/pubmed/31147716
http://dx.doi.org/10.1093/nar/gkz482

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