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Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase

Replicative DNA polymerases are highly efficient enzymes that maintain stringent geometric control over shape and orientation of the template and incoming nucleoside triphosphate. In a surprising twist to this paradigm, a naturally occurring bacterial DNA polymerase I member isolated from Geobacillu...

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Detalles Bibliográficos
Autores principales: Jackson, Lynnette N, Chim, Nicholas, Shi, Changhua, Chaput, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649750/
https://www.ncbi.nlm.nih.gov/pubmed/31170294
http://dx.doi.org/10.1093/nar/gkz513