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Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase
Replicative DNA polymerases are highly efficient enzymes that maintain stringent geometric control over shape and orientation of the template and incoming nucleoside triphosphate. In a surprising twist to this paradigm, a naturally occurring bacterial DNA polymerase I member isolated from Geobacillu...
Autores principales: | Jackson, Lynnette N, Chim, Nicholas, Shi, Changhua, Chaput, John C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649750/ https://www.ncbi.nlm.nih.gov/pubmed/31170294 http://dx.doi.org/10.1093/nar/gkz513 |
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