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Limits to a classic paradigm: most transcription factors in E. coli regulate genes involved in multiple biological processes

Transcription factors (TFs) are important drivers of cellular decision-making. When bacteria encounter a change in the environment, TFs alter the expression of a defined set of genes in order to adequately respond. It is commonly assumed that genes regulated by the same TF are involved in the same b...

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Detalles Bibliográficos
Autores principales: Ledezma-Tejeida, Daniela, Altamirano-Pacheco, Luis, Fajardo, Vicente, Collado-Vides, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649764/
https://www.ncbi.nlm.nih.gov/pubmed/31194874
http://dx.doi.org/10.1093/nar/gkz525