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Imprecise Kidney Function Thresholds in Cancer Clinical Trials and the Potential for Harm

Current guidance for evaluation of kidney function and drug dosing emphasize using measured or estimated glomerular filtration rate (GFR) rather than measured or estimated creatinine clearance or serum creatinine (Scr) alone. We assessed the definitions of kidney function thresholds for eligibility...

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Detalles Bibliográficos
Autores principales: Wang, Edwin, Paulus, Jessica K, Hackenyos, Douglas, Inker, Lesley A, Levey, Andrew S, Mathew, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649787/
https://www.ncbi.nlm.nih.gov/pubmed/31360878
http://dx.doi.org/10.1093/jncics/pky060