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A Mn-sensing riboswitch activates expression of a Mn(2+)/Ca(2+) ATPase transporter in Streptococcus

Maintaining manganese (Mn) homeostasis is important for the virulence of numerous bacteria. In the human respiratory pathogen Streptococcus pneumoniae, the Mn-specific importer PsaBCA, exporter MntE, and transcriptional regulator PsaR establish Mn homeostasis. In other bacteria, Mn homeostasis is co...

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Detalles Bibliográficos
Autores principales: Martin, Julia E, Le, My T, Bhattarai, Nabin, Capdevila, Daiana A, Shen, Jiangchuan, Winkler, Malcolm E, Giedroc, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649816/
https://www.ncbi.nlm.nih.gov/pubmed/31165873
http://dx.doi.org/10.1093/nar/gkz494