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Identification of DNA motifs that regulate DNA methylation

DNA methylation is an important epigenetic mark but how its locus-specificity is decided in relation to DNA sequence is not fully understood. Here, we have analyzed 34 diverse whole-genome bisulfite sequencing datasets in human and identified 313 motifs, including 92 and 221 associated with methylat...

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Detalles Bibliográficos
Autores principales: Wang, Mengchi, Zhang, Kai, Ngo, Vu, Liu, Chengyu, Fan, Shicai, Whitaker, John W, Chen, Yue, Ai, Rizi, Chen, Zhao, Wang, Jun, Zheng, Lina, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649826/
https://www.ncbi.nlm.nih.gov/pubmed/31334813
http://dx.doi.org/10.1093/nar/gkz483