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Development of an evidence-based regimen of prednisolone to treat giant cell arteritis – the Norwich regimen

We have reviewed the literature to form a bespoke regimen for daily oral prednisolone (DP) in GCA. Initial DP in clinical trials is 40–60 mg daily, but relapse rates are 67–92%. Cumulative prednisolone (CP) of 3.2 and 3.9 g (at 6 months) resulted in a relapse rate of 83 and 67%, respectively; and 3...

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Detalles Bibliográficos
Autores principales: Mukhtyar, Chetan, Cate, Heidi, Graham, Conor, Merry, Peter, Mills, Karen, Misra, Aseema, Jones, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649920/
https://www.ncbi.nlm.nih.gov/pubmed/31431989
http://dx.doi.org/10.1093/rap/rkz001