IL23R gene variants in relation to IL17A levels and clinical phenotype in patients with ankylosing spondylitis

BACKGROUND: IL23 receptor (IL23R) binding by IL23 is required for the maturation of CD4(+) cells into Th17 cells and subsequent generation of IL17A and TNF. As IL23R variations contribute to AS susceptibility, we investigated the effect of IL23R variants on cytokine levels and disease measures in an...

Descripción completa

Detalles Bibliográficos
Autores principales: Nossent, Johannes C, Sagen-Johnsen, Sylvia, Bakland, Gunnstein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Consice Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649922/
https://www.ncbi.nlm.nih.gov/pubmed/31431955
http://dx.doi.org/10.1093/rap/rky006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649922/
https://www.ncbi.nlm.nih.gov/pubmed/31431955
http://dx.doi.org/10.1093/rap/rky006

Ejemplares similares