Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials

OBJECTIVE: Adaptive designs can enable highly sophisticated and efficient early phase trials, but the clinical inference from these trials is surrounded by complexity, and currently there is a paucity but steadily increasing amount of use of these designs in all fields of medicine. We aim to review...

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Detalles Bibliográficos
Autores principales: Pickles, Tim, Christensen, Robin, Tam, Lai-Shan, Simon, Lee S, Choy, Ernest H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649924/
https://www.ncbi.nlm.nih.gov/pubmed/31431982
http://dx.doi.org/10.1093/rap/rky045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649924/
https://www.ncbi.nlm.nih.gov/pubmed/31431982
http://dx.doi.org/10.1093/rap/rky045

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