Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma

This case of a radiation-naive patient with pilocytic astrocytoma highlights how deletions of CDKN2A (cyclin-dependent kinase Inhibitor 2A) and PTEN (phosphatase and tensin homolog) portended a poor clinical outcome. Pilocytic astrocytomas are grade 1 tumors usually occurring in children and young a...

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Detalles Bibliográficos
Autores principales: Cagney, Daniel N, Miller, Michael B, Dubuc, Adrian, Delalle, Ivana, Ligon, Azra H, Chukwueke, Ugonma, Al-Mefty, Ossama, Aizer, Ayal, Ligon, Keith, Wen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649926/
https://www.ncbi.nlm.nih.gov/pubmed/31355086
http://dx.doi.org/10.7759/cureus.4726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649926/
https://www.ncbi.nlm.nih.gov/pubmed/31355086
http://dx.doi.org/10.7759/cureus.4726

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