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Optimal use of statistical methods to validate reference gene stability in longitudinal studies

Multiple statistical approaches have been proposed to validate reference genes in qPCR assays. However, conflicting results from these statistical methods pose a major hurdle in the choice of the best reference genes. Recent studies have proposed the use of at least three different methods but there...

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Detalles Bibliográficos
Autores principales: Sundaram, Venkat Krishnan, Sampathkumar, Nirmal Kumar, Massaad, Charbel, Grenier, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650036/
https://www.ncbi.nlm.nih.gov/pubmed/31335863
http://dx.doi.org/10.1371/journal.pone.0219440