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Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study

Recent evidence has raised in discussion the possibility that cannabidiol can act as a negative allosteric modulator of the cannabinoid type 1 receptor. Here we have used computational methods to study the modulation exerted by cannabidiol on the effects of delta-9-tetrahydrocannabinol in the cannab...

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Detalles Bibliográficos
Autores principales: Chung, Hery, Fierro, Angélica, Pessoa-Mahana, C. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650144/
https://www.ncbi.nlm.nih.gov/pubmed/31335889
http://dx.doi.org/10.1371/journal.pone.0220025