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CDK12 inactivation across solid tumors: an actionable genetic subtype

Inactivating CDK12 alterations have been reported in ovarian and prostate cancers and may have therapeutic implications; however, the prevalence of these mutations across other cancer types is unknown. We searched the cBioPortal and GENIE Project (public release v4.1) databases for cancer types with...

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Detalles Bibliográficos
Autores principales: Marshall, Catherine H., Imada, Eddie L., Tang, Zhuojun, Marchionni, Luigi, Antonarakis, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650168/
https://www.ncbi.nlm.nih.gov/pubmed/31360735
http://dx.doi.org/10.18632/oncoscience.481