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Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections

The complement system is pivotal in the defense against invasive disease caused by Neisseria meningitidis (Nme, meningococcus), particularly via the membrane attack complex. Complement activation liberates the anaphylatoxins C3a and C5a, which activate three distinct G-protein coupled receptors, C3a...

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Detalles Bibliográficos
Autores principales: Muenstermann, Marcel, Strobel, Lea, Klos, Andreas, Wetsel, Rick A., Woodruff, Trent M., Köhl, Jörg, Johswich, Kay O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650196/
https://www.ncbi.nlm.nih.gov/pubmed/31274379
http://dx.doi.org/10.1080/21505594.2019.1640035