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Predictable fibroblast tension generation by measuring compaction of anchored collagen matrices using microscopy and optical coherence tomography

The anchored fibroblast-populated collagen matrix (aFPCM) is an appropriate model to study fibrocontractive disease mechanisms. Our goal was to determine if aFPCM height reduction (compaction) during development is sufficient to predict tension generation. Compaction was quantified daily by both tra...

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Detalles Bibliográficos
Autores principales: Vaughan, Melville B., Xu, Gang, Morris, Tracy L., Kshetri, Pratiksha, Herwig, Jing X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650198/
https://www.ncbi.nlm.nih.gov/pubmed/31331232
http://dx.doi.org/10.1080/19336918.2019.1644855