Multi-enhancer transcriptional hubs confer phenotypic robustness

We previously showed in Drosophila melanogaster embryos that low-affinity Ultrabithorax (Ubx)-responsive shavenbaby (svb) enhancers drive expression using localized transcriptional environments and that active svb enhancers on different chromosomes tended to colocalize (Tsai et al., 2017). Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Albert, Alves, Mariana RP, Crocker, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650246/
https://www.ncbi.nlm.nih.gov/pubmed/31294690
http://dx.doi.org/10.7554/eLife.45325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650246/
https://www.ncbi.nlm.nih.gov/pubmed/31294690
http://dx.doi.org/10.7554/eLife.45325

Ejemplares similares