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Multi-enhancer transcriptional hubs confer phenotypic robustness

We previously showed in Drosophila melanogaster embryos that low-affinity Ultrabithorax (Ubx)-responsive shavenbaby (svb) enhancers drive expression using localized transcriptional environments and that active svb enhancers on different chromosomes tended to colocalize (Tsai et al., 2017). Here, we...

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Detalles Bibliográficos
Autores principales:	Tsai, Albert, Alves, Mariana RP, Crocker, Justin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650246/ https://www.ncbi.nlm.nih.gov/pubmed/31294690 http://dx.doi.org/10.7554/eLife.45325

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