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Local nascent protein deposition and remodeling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels
Hydrogels serve as valuable tools for studying cell-extracellular matrix (ECM) interactions in three-dimensional (3D) environments that recapitulate aspects of native ECM. However, the impact of early protein deposition on cell behavior within hydrogels has largely been overlooked. Using a bio-ortho...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650309/ https://www.ncbi.nlm.nih.gov/pubmed/30886401 http://dx.doi.org/10.1038/s41563-019-0307-6 |