Untargeted Metabolomic Profiling Reveals Multiple Pathway Perturbations and New Clinical Biomarkers in Urea Cycle Disorders

PURPOSE: Untargeted metabolomic analysis is increasingly being used in the screening and management of individuals with inborn errors of metabolism (IEM). We aimed to test whether untargeted metabolomic analysis in plasma might be useful for monitoring the disease course and management of urea cycle...

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Detalles Bibliográficos
Autores principales: Burrage, Lindsay C., Thistlethwaite, Lillian, Stroup, Bridget M., Sun, Qin, Miller, Marcus J., Nagamani, Sandesh CS, Craigen, William, Scaglia, Fernando, Sutton, V. Reid, Graham, Brett, Kennedy, Adam D., Milosavljevic, Aleksandar, Lee, Brendan H., Elsea, Sarah H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650380/
https://www.ncbi.nlm.nih.gov/pubmed/30670878
http://dx.doi.org/10.1038/s41436-019-0442-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650380/
https://www.ncbi.nlm.nih.gov/pubmed/30670878
http://dx.doi.org/10.1038/s41436-019-0442-0

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