Cargando…

A collagen-based microwell migration assay to study NK-target cell interactions

Natural killer (NK) cell cytotoxicity in tissue is dependent on the ability of NK cells to migrate through the extracellular matrix (ECM) microenvironment. Traditional imaging studies of NK cell migration and cytotoxicity have utilized 2D surfaces, which do not properly reproduce the structural and...

Descripción completa

Detalles Bibliográficos
Autores principales: Olofsson, Per E., Brandt, Ludwig, Magnusson, Klas E. G., Frisk, Thomas, Jaldén, Joakim, Önfelt, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650390/
https://www.ncbi.nlm.nih.gov/pubmed/31337806
http://dx.doi.org/10.1038/s41598-019-46958-3