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Coupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells

A properly functioning immune system is vital for an organism’s wellbeing. Immune tolerance is a critical feature of the immune system that allows immune cells to mount effective responses against exogenous pathogens such as viruses and bacteria, while preventing attack to self-tissues. Activation-i...

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Detalles Bibliográficos
Autores principales: Shin, Sung-Young, Kim, Min-Wook, Cho, Kwang-Hyun, Nguyen, Lan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650396/
https://www.ncbi.nlm.nih.gov/pubmed/31337782
http://dx.doi.org/10.1038/s41598-019-46592-z