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Modeling the binding of diverse ligands within the Ah receptor ligand binding domain

The Ah receptor (AhR) is a ligand-dependent transcription factor belonging to the basic helix-loop-helix Per-Arnt-Sim (bHLH-PAS) superfamily. Binding to and activation of the AhR by a variety of chemicals results in the induction of expression of diverse genes and production of a broad spectrum of b...

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Detalles Bibliográficos
Autores principales: Giani Tagliabue, Sara, Faber, Samantha C., Motta, Stefano, Denison, Michael S., Bonati, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650409/
https://www.ncbi.nlm.nih.gov/pubmed/31337850
http://dx.doi.org/10.1038/s41598-019-47138-z